Wholesale · Cosmetic peptide
Wholesale Syn-Ake peptide
A fully synthetic cosmetic peptide — INCI Dipeptide Diaminobutyroyl Benzylamide Diacetate — working through a different receptor pathway from the SNAP-25 peptides. Manufactured to GMP standard at ≥98% HPLC purity with a batch COA included, and supplied wholesale and white label across Europe and internationally.
≥98% HPLC puritySynthetic, non-animalWater soluble
GMP · ISO · HACCPUK & Berlin manufacturingThird-party testedManufacturer direct since 2018
Overview
A third route to the same category
Different receptor
Acts at the nicotinic acetylcholine receptor, not on SNAP-25.
Fully synthetic
No animal-derived material — suits vegan and cruelty-free positioning.
Water soluble
Straightforward in aqueous serums, unlike palmitoylated peptides.
It is not snake venom — and that matters commercially
Syn-Ake is frequently described online as a "snake venom peptide". That is inaccurate and, for a brand, unhelpful. The material is a synthetic peptide designed to resemble a component found in temple viper venom; it is produced by peptide synthesis and contains no venom and no animal-derived input. For brands pursuing vegan or cruelty-free certification, this is a point worth stating correctly on your own product pages — the synthetic origin is an advantage, not a caveat.Syn-Ake is a trade name for Dipeptide Diaminobutyroyl Benzylamide Diacetate, a synthetic cosmetic peptide originated by Pentapharm. It was designed to mimic the structure of Waglerin-1, a peptide identified in the venom of the temple viper — but the material itself is manufactured synthetically and contains no animal-derived component.Commercially it occupies the same expression-line space as Argireline and SNAP-8, but reaches it by a different route. Those two act on SNAP-25 within the SNARE complex; Syn-Ake acts at the nicotinic acetylcholine receptor. For brands, that difference supports a multi-pathway formulation story rather than duplicating an existing claim.SARMs Direct supplies wholesale Syn-Ake peptide to skincare brands, cosmetic manufacturers, ingredient distributors, formulation laboratories and private label buyers. All supply is GMP-certified with full batch documentation and a COA included.
Compound specifications
Syn-Ake at a glance
| Product name | Syn-Ake (trade name) |
| INCI name | Dipeptide Diaminobutyroyl Benzylamide Diacetate |
| CAS number | 823202-99-9 |
| Compound class | Synthetic cosmetic dipeptide (diacetate salt) |
| Molecular weight | ≈507.6 g/mol (as diacetate) |
| Design basis | Structural mimic of Waglerin-1 |
| Origin | Fully synthetic — no animal-derived material |
| Purity | ≥98% (HPLC verified) |
| Appearance | White to off-white powder |
| Solubility | Water soluble |
| Storage | Cool, dry place. Protect from light and moisture. Refrigerate for long-term storage. |
Available quantities
Supply options
1g
Sample / trial
10g
Small batch
100g
Standard
1kg+
Bulk
- Powder or solution — solution simplifies dosing given the low use levels involved.
- Standard quantities from 1g to 1kg and larger bulk, with custom quotations by volume and supply frequency.
- White & private label supply for skincare brands and cosmetic manufacturers.
- Samples available for formulation trials — mention it in your enquiry.
Building a peptide range
Three routes into the expression-line category
| Syn-Ake | Dipeptide Diaminobutyroyl Benzylamide Diacetate |
| Argireline | Acetyl Hexapeptide-8 |
| SNAP-8 | Acetyl Octapeptide-3 |
ⓘ For collagen-support mechanisms see Matrixyl and Matrixyl 3000; for copper chemistry see GHK-Cu.
For your formulators
Formulation considerations
Working with Syn-Ake
- Water soluble and easy to handle. Suits aqueous serums, essences, gels and lightweight emulsions — considerably simpler than the palmitoylated peptides.
- Colourless. No tinting, unlike GHK-Cu.
- Low use levels. A pre-diluted solution removes weighing error at production scale.
- Add in the cool-down phase. Avoid prolonged high-temperature processing, as with peptides generally.
- Combines cleanly with SNAP-25 peptides. Different receptor, no known conflict — the basis of multi-pathway serum formulations.
General formulation guidance only. Use levels, stability and compatibility should be validated in your own formulation and stability testing. "Syn-Ake" is a third-party trade name; we supply the material by INCI designation. Responsibility for finished-product claims and labelling rests with the brand owner.
Formulation applications
Where Syn-Ake is used
- Anti-ageing serums targeting expression lines
- Eye creams and periorbital treatments
- Forehead and frown line products
- Multi-pathway peptide complexes
- Vegan and cruelty-free certified skincare lines
- Sheet masks and treatment ampoules
- Private label and white label skincare products
Quality & documentation
Every batch documented
- GMP-certified manufacturing
- ISO quality management system
- HACCP-compliant production controls
- Independent third-party HPLC testing
- Certificate of Analysis (COA) issued per batch
- MSDS available on request
- Full batch and lot traceability records
Who orders wholesale Syn-Ake
Built for cosmetic B2B buyers
Skincare brands
Expression-line and multi-pathway product formulation.
Vegan & cruelty-free brands
Synthetic origin suits certification requirements.
Private label companies
White label peptide skincare ranges.
Cosmetic manufacturers
Ingredient supply for production runs.
Ingredient distributors
Regional distribution of cosmetic peptides.
Formulation laboratories
R&D and prototype development.
Related cosmetic peptides
Buyers of Syn-Ake also order
Sourcing more than one cosmetic peptide? We supply multi-peptide orders on a single quotation and single shipment — mention the full list in your enquiry and we'll price it together. For the wider peptide range, see our sister site Peptide-Direct →
Request a wholesale Syn-Ake quote
Tell us whether you need powder or solution, your target quantity, and any other peptides you're sourcing. We'll reply within 24 hours with pricing and a current batch COA on request.
Frequently asked questions
Is Syn-Ake made from snake venom?
No. It is a fully synthetic peptide designed to mimic the structure of Waglerin-1, a peptide identified in temple viper venom. The material is produced by peptide synthesis and contains no venom and no animal-derived input, which is why it suits vegan and cruelty-free certified product lines.
What is the INCI name and CAS number?
The INCI name is Dipeptide Diaminobutyroyl Benzylamide Diacetate and the CAS number is 823202-99-9. Molecular weight is approximately 507.6 g/mol as the diacetate salt.
How does it differ from Argireline and SNAP-8?
Different receptor pathway. Argireline and SNAP-8 act on SNAP-25 within the SNARE complex; Syn-Ake acts at the nicotinic acetylcholine receptor. All three are positioned around expression lines, and brands commonly combine them for a multi-pathway formulation.
Is it water soluble?
Yes. It is water soluble and straightforward to formulate into aqueous serums, essences and lightweight emulsions — considerably simpler than the palmitoylated peptides such as Matrixyl.
What quantities is wholesale Syn-Ake available in?
1g, 10g, 100g, 1kg and larger bulk quantities, as powder or pre-diluted solution. Custom quotations are available based on volume and supply frequency, and samples can be supplied for formulation trials.
Do you offer white label Syn-Ake supply?
Yes. White label and private label supply is available for skincare brands and cosmetic manufacturers. Contact us to discuss formulation, packaging and volume requirements.
Supplied for cosmetic formulation and laboratory research purposes. Not for human consumption. Buyers are responsible for ensuring finished products comply with applicable cosmetics regulations in their market.