Wholesale · Cosmetic peptide
Wholesale Argireline (Acetyl Hexapeptide-8)
The most widely used expression-line peptide in cosmetic formulation, manufactured to GMP standard at ≥98% HPLC purity with a batch COA included. Supplied wholesale and white label — as powder or aqueous solution — to skincare brands, cosmetic manufacturers and formulation laboratories across Europe and internationally.
≥98% HPLC purityPowder or solution1g to 1kg+
GMP · ISO · HACCPUK & Berlin manufacturingThird-party testedManufacturer direct since 2018
Overview
The category-defining expression-line peptide
Category benchmark
The most widely formulated expression-line peptide in the market.
Consumer recognition
One of the few peptide names consumers actively search by.
Two formats
Supplied as powder or as a ready-to-dose aqueous solution.
Argireline is the trade name for Acetyl Hexapeptide-8 — a synthetic six amino acid cosmetic peptide originated by Lipotec, and the compound that effectively created the expression-line peptide category. It remains the most widely formulated peptide of its type and carries strong recognition with both formulators and end consumers.Its sequence corresponds to the N-terminal end of SNAP-25, a protein involved in neurotransmitter release at the neuromuscular junction. This is the same target as SNAP-8, which is the extended eight amino acid analogue developed after it.SARMs Direct supplies wholesale Argireline as powder or aqueous solution to skincare brands, cosmetic manufacturers, ingredient distributors, formulation laboratories and private label buyers. All supply is GMP-certified with full batch documentation and a COA included.
Compound specifications
Argireline at a glance
| Product name | Argireline (trade name) |
| INCI name | Acetyl Hexapeptide-8 |
| Former INCI | Acetyl Hexapeptide-3 (still widely used) |
| CAS number | 616204-22-9 |
| Compound class | Synthetic cosmetic peptide (hexapeptide) |
| Sequence | Ac-Glu-Glu-Met-Gln-Arg-Arg-NH₂ |
| Molecular formula | C₃₄H₆₀N₁₄O₁₂S |
| Molecular weight | ≈888.99 g/mol |
| Purity | ≥98% (HPLC verified) |
| Appearance | White to off-white powder |
| Solubility | Water soluble |
| Storage | Cool, dry place. Protect from light and moisture. Refrigerate for long-term storage. |
Available quantities
Supply options
1g
Sample / trial
10g
Small batch
100g
Standard
1kg+
Bulk
- Powder or aqueous solution — specify which you need. Solution concentration to your requirement.
- Standard quantities from 1g to 1kg and larger bulk, with custom quotations by volume and supply frequency.
- White & private label supply for skincare brands and cosmetic manufacturers.
- Samples available for formulation trials — mention it in your enquiry.
Choosing between them
Argireline or SNAP-8?
| INCI | Acetyl Hexapeptide-8 |
| Length | 6 amino acids |
| Target | SNAP-25 (N-terminal) |
| Market position | Category benchmark, high consumer recognition |
| Typical use | Broad range, mass to prestige |
| Page | This page |
ⓘ Many brands formulate both together in multi-peptide complexes. We can quote them on a single order.
For your formulators
Formulation considerations
Working with Argireline
- Water soluble and straightforward. It suits aqueous serums, essences, gels and lightweight emulsions, and is considerably easier to formulate with than copper peptides.
- Colourless. Unlike GHK-Cu it will not tint your base — useful when you want a clear or white finished product.
- Powder or solution. Powder gives you control over concentration; a ready-made aqueous solution simplifies dosing on the production line. Tell us which suits your process.
- Add in the cool-down phase. As with most peptides, avoid prolonged exposure to high processing temperatures.
- Pairs well in multi-peptide complexes. Commonly formulated alongside SNAP-8, Matrixyl-type peptides and copper peptides in booster serums.
A note on marketing claims
Argireline is frequently marketed with comparisons to injectable procedures. In most jurisdictions — including the UK and EU — that framing risks presenting a cosmetic as having a medicinal or device-like action, which is a regulated claim and a common cause of advertising complaints. We supply the ingredient with accurate technical documentation and would encourage you to keep finished-product claims within cosmetic boundaries, focused on appearance and skin feel. Responsibility for finished-product claims rests with the brand owner.Formulation applications
Where Argireline is used
- Anti-ageing facial serums targeting expression lines
- Eye creams for periorbital lines
- Forehead and frown line treatments
- Peptide moisturisers across mass and prestige tiers
- Multi-peptide complexes and booster serums
- Sheet masks and treatment ampoules
- Private label and white label skincare products
Quality & documentation
Every batch documented
- GMP-certified manufacturing
- ISO quality management system
- HACCP-compliant production controls
- Independent third-party HPLC testing
- Certificate of Analysis (COA) issued per batch
- MSDS available on request
- Full batch and lot traceability records
Who orders wholesale Argireline
Built for cosmetic B2B buyers
Skincare brands
Expression-line and anti-ageing product formulation.
Private label companies
White label peptide skincare ranges.
Cosmetic manufacturers
Ingredient supply for production runs.
Ingredient distributors
Regional distribution of cosmetic peptides.
Formulation laboratories
R&D and prototype development.
E-commerce beauty brands
Direct-to-consumer peptide skincare.
Related cosmetic peptides
Buyers of Argireline also order
SNAP-8 (Acetyl Octapeptide-3) →The eight amino acid analogue — premium positioning, same target.GHK-Cu (Copper Tripeptide-1) →The benchmark copper peptide for premium skincare formulation.
Sourcing more than one cosmetic peptide? We supply multi-peptide orders on a single quotation and single shipment — mention the full list in your enquiry and we'll price it together. For the wider peptide range, see our sister site Peptide-Direct →
Request a wholesale Argireline quote
Tell us whether you need powder or solution, your target quantity, and whether you need white label. We'll reply within 24 hours with pricing and a current batch COA on request.
Frequently asked questions
What is Argireline?
Argireline is the trade name for Acetyl Hexapeptide-8, a synthetic six amino acid cosmetic peptide originated by Lipotec. Its sequence corresponds to the N-terminal end of SNAP-25, and it is the most widely formulated expression-line peptide in cosmetic products.
Is Acetyl Hexapeptide-8 the same as Acetyl Hexapeptide-3?
Yes — they refer to the same material. Acetyl Hexapeptide-3 was the earlier INCI designation and Acetyl Hexapeptide-8 is the current one. Both names remain in circulation in trade literature and on ingredient lists.
What is the CAS number for Argireline?
The CAS number is 616204-22-9. The molecular formula is C₃₄H₆₀N₁₄O₁₂S with a molecular weight of approximately 888.99 g/mol.
What is the difference between Argireline and SNAP-8?
Both target SNAP-25. Argireline is a six amino acid peptide and the established category benchmark; SNAP-8 is the eight amino acid analogue developed later and is generally positioned as the premium option. Many brands formulate both together in multi-peptide complexes.
Do you supply Argireline as a solution or powder?
Both. Powder gives you control over concentration in your own formulation; a ready-made aqueous solution simplifies dosing on the production line. Specify which you need in your enquiry and we'll quote accordingly.
Do you offer white label Argireline supply?
Yes. White label and private label supply is available for skincare brands and cosmetic manufacturers. Contact us to discuss formulation, packaging and volume requirements.
Supplied for cosmetic formulation and laboratory research purposes. Not for human consumption. Buyers are responsible for ensuring finished products comply with applicable cosmetics regulations in their market.